How does a fungal pathogen know it’s inside the host?

We’re excited to share our latest findings on how the maize pathogen Ustilago maydis senses when it has entered its plant host. In this study, we discovered a new GPCR-based system that links host protease activity to fungal signaling, allowing the pathogen to recognize the host environment and trigger infection-related responses. This work, led by Gabriel and Philip, uncovers the Gpe1–Pit2 system as a key example of how fungi translate host-derived cues into developmental decisions during infection.

Read the preprint here

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